Manifold Bio
Tissue-targeted medicines, designed in vivo.
Manifold Bio is positioned to be the leading tissue-specific medicines company. We’ve built the first high-throughput in vivo (HTV) discovery engine - combining massively multiplexed in vivo screening and AI-powered design to create targeted biologics. Our engine sculpts pharmacokinetics, biodistribution, and other key properties of biologics directly in living systems, solving previously intractable challenges for tissue-specific delivery.

Research Associate, Protein Sciences (Temporary 4-6 months)
Boston · Posted on Jan 9, 2026

Associate Scientist/Senior Associate Scientist, Protein Sciences
Boston · Posted on Jan 8, 2026

Director, People & Talent Operations
Boston · Posted on Jan 6, 2026

Senior Research Associate, Shuttled Oligo Therapeutics
Boston · Posted on Dec 10, 2025

Head of Biotherapeutics
Boston · Posted on Dec 8, 2025

Bioinformatics Engineer
Boston · Posted on Dec 3, 2025

Project Team Lead
Boston · Posted on Aug 2, 2025









