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Manifold Bio

Tissue-targeted medicines, designed in vivo.

Manifold Bio is positioned to be the leading tissue-specific medicines company. We’ve built the first high-throughput in vivo (HTV) discovery engine - combining massively multiplexed in vivo screening and AI-powered design to create targeted biologics. Our engine sculpts pharmacokinetics, biodistribution, and other key properties of biologics directly in living systems, solving previously intractable challenges for tissue-specific delivery.